MYOM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38603

Novus Biologicals, part of Bio-Techne
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NBP2-38603
NBP2-38603-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MYOM1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: FDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MYOM1 Antibody

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603]

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603]

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603] - Staining of human skeletal muscle shows cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603]

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603]

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603] - Analysis in human heart muscle and pancreas tissues. Corresponding MYOM1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603]

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603]

Immunohistochemistry-Paraffin: MYOM1 Antibody [NBP2-38603] - Staining of human heart muscle, pancreas, prostate and skeletal muscle using Anti-MYOM1 antibody NBP2-38603 (A) shows similar protein distribution across tissues to independent antibody NBP1-86460 (B).
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Applications for MYOM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MYOM1

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Alternate Names

190 kDa connectin-associated protein, 190 kDa titin-associated protein, EH-myomesin, MGC134946, MGC134947, myomesin (M-protein) 1 (190kD), myomesin 1 (skelemin) (185kD), myomesin 1 (skelemin) 185kDa, myomesin 1, 185kDa, Myomesin family member 1, myomesin-1, SKELEMIN

Gene Symbol

MYOM1

UniProt

P52179 (Human)

Additional MYOM1 Products

Product Documents for MYOM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MYOM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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