Myotubularin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86113

Novus Biologicals, part of Bio-Techne
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NBP1-86113
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Myotubularin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KFNVDGWTVYNPVEEYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (84%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myotubularin Antibody

Immunocytochemistry/ Immunofluorescence: Myotubularin Antibody [NBP1-86113]

Immunocytochemistry/ Immunofluorescence: Myotubularin Antibody [NBP1-86113]

Immunocytochemistry/Immunofluorescence: Myotubularin Antibody [NBP1-86113] - Staining of human cell line U-251 MG shows localization to plasma membrane.
Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113]

Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113]

Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human testis shows moderate to strong cytoplasmic positivity in subsets of cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113]

Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113]

Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human fallopian tube shows moderate to strong membranous positivity in subsets of glandular cells.
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Applications for Myotubularin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myotubularin

MTM1 encodes a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. It is required for muscle cell differentiation and mutations in this gene have been identified as being responsible for X-linked myotubular myopathy.

Alternate Names

CG2, CNM, EC 3.1.3.48, MTMX, myotubular myopathy 1, myotubularin, myotubularin 1, XLMTM

Gene Symbol

MTM1

Additional Myotubularin Products

Product Documents for Myotubularin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Myotubularin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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