Myt1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81021

Novus Biologicals, part of Bio-Techne
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NBP1-81021
NBP1-81021-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Myt1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPLDT

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (81%). Mouse reactivity reported in scientific literature (PMID: 26607952).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myt1 Antibody

Immunocytochemistry/ Immunofluorescence: Myt1 Antibody [NBP1-81021]

Immunocytochemistry/ Immunofluorescence: Myt1 Antibody [NBP1-81021]

Immunocytochemistry/Immunofluorescence: Myt1 Antibody [NBP1-81021] - Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: Myt1 Antibody [NBP1-81021]

Immunohistochemistry-Paraffin: Myt1 Antibody [NBP1-81021]

Immunohistochemistry-Paraffin: Myt1 Antibody [NBP1-81021] - Staining of human cerebellum shows moderate nuclear positivity in cells in granular layer.

Applications for Myt1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. IP reported in the scientific literature (PMID: 26607952).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myt1

MYT1, also known as Myelin transcription factor 1, consists of a long 1,121 amino acid isoform that is 122 kDa, and is involved in the development of the central nervous system and the regulation of oligodendrocyte lineage development. Current research is being conducted on the relationship between MYT1 and a variety of diseases and disorders, including multiple sclerosis, papillary thyroid carcinoma, leukomalacia, neuronitis, sporadic breast cancer, skin cancer, pancreatitis, schizophrenia, thyroiditis, and carcinoma. The protein interacts with SIN3B, PIN1, PLK1, HDAC1, and CDK1, and has been linked to pancreatic and breast cancer pathways, as well as G1 to S cell cycle control.

Long Name

Myelin transcription factor 1

Alternate Names

KIAA0835, KIAA1050, MTF1, MyTI, PLPB1

Entrez Gene IDs

4661 (Human)

Gene Symbol

MYT1

UniProt

Q01538 (Human)

Additional Myt1 Products

Product Documents for Myt1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Myt1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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