NAIP Antibody (SR1227)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22296

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22296-100ul
NBP3-22296-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1227

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NAIP Antibodies »

Product Summary for NAIP Antibody (SR1227)

Immunogen

A synthesized peptide derived from human NAIP (Uniprot #: Q13075)

Specificity

Detects endogenous levels of total NAIP

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NAIP Antibody (SR1227)

Western Blot: NAIP Antibody (SR1227) [NBP3-22296] -

Western Blot: NAIP Antibody (SR1227) [NBP3-22296] - Western blot analysis using NBP3-22296 in Human fetal kidney lysate.

Applications for NAIP Antibody (SR1227)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NAIP

Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.

Long Name

Neuronal Apoptosis Inhibitor Protein

Alternate Names

BIRC1, NLRB1

Gene Symbol

NAIP

Additional NAIP Products

Product Documents for NAIP Antibody (SR1227)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NAIP Antibody (SR1227)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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