NANS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31440

Novus Biologicals, part of Bio-Techne
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NBP1-31440
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (97%), Mouse (97%), Porcine (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NANS Antibodies »

Product Summary for NANS Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human NANS. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NANS Antibody

Western Blot: NANS Antibody [NBP1-31440]

Western Blot: NANS Antibody [NBP1-31440]

Western Blot: NANS Antibody [NBP1-31440] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE NANS antibody, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: NANS Antibody [NBP1-31440]

Immunocytochemistry/ Immunofluorescence: NANS Antibody [NBP1-31440]

Immunocytochemistry/Immunofluorescence: NANS Antibody [NBP1-31440] - Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: NANS protein stained by NANS antibody diluted at 1:500.Blue: Hoechst 33342 staining. Scale bar = 10 um.
Immunohistochemistry-Paraffin: NANS Antibody [NBP1-31440]

Immunohistochemistry-Paraffin: NANS Antibody [NBP1-31440]

Immunohistochemistry-Paraffin: NANS Antibody [NBP1-31440] - Paraffin-embedded normal gastric epithelium (gland), using antibody at 1:100 dilution.

Applications for NANS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NANS

This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Alternate Names

EC 2.5.1.56, EC 2.5.1.57, N-acetylneuraminate synthase, N-acetylneuraminate-9-phosphate synthase, N-acetylneuraminic acid phosphate synthase, N-acetylneuraminic acid synthasesialic acid phosphate synthase, SASsialic acid synthase

Gene Symbol

NANS

Additional NANS Products

Product Documents for NANS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NANS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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