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NAPRT1 Antibody (CL0366)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52924

Novus Biologicals, part of Bio-Techne
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NBP2-52924
NBP2-52924-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL0366

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for NAPRT1 Antibody (CL0366)

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LLDTYSVWRSGLPNFLAVALALGELGYRAVGVRLDSGDLLQQAQEIRKVFRAAAAQFQVPWLESVLIVVSNNIDEEALARLAQEGSEVNVIGIGTSV

Epitope

IRKVFRAAAA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (82%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for NAPRT1 Antibody (CL0366)

Western Blot: NAPRT1 Antibody (CL0366) [NBP2-52924]

Western Blot: NAPRT1 Antibody (CL0366) [NBP2-52924]

Western Blot: NAPRT1 Antibody (CL0366) [NBP2-52924] - Lane 1: Marker [kDa], Lane 2: Human liver tissue lysate
Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0366) [NBP2-52924]

Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0366) [NBP2-52924]

Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0366) [NBP2-52924] - Staining of human testis shows strong positivity in the seminiferous ducts.
Immunohistochemistry: NAPRT1 Antibody (CL0366) [NBP2-52924]

Immunohistochemistry: NAPRT1 Antibody (CL0366) [NBP2-52924]

Immunohistochemistry: NAPRT1 Antibody (CL0366) [NBP2-52924] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Applications for NAPRT1 Antibody (CL0366)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NAPRT1

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM]

Alternate Names

EC 2.4.2.11, FHA-HIT-interacting protein, FHIP, NAPRTase, nicotinate phosphoribosyltransferase, nicotinate phosphoribosyltransferase domain containing 1, Nicotinate phosphoribosyltransferase domain-containing protein 1, nicotinic acid phosphoribosyltransferase, PP3856

Gene Symbol

NAPRT

Additional NAPRT1 Products

Product Documents for NAPRT1 Antibody (CL0366)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NAPRT1 Antibody (CL0366)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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