NAT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59905

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all NAT2 Antibodies »

Product Summary for NAT2 Antibody

Immunogen

Synthetic peptides corresponding to NAT2(N-acetyltransferase 2 (arylamine N-acetyltransferase)) The peptide sequence was selected from the middle region of NAT2. Peptide sequence CLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPRTIE. The peptide sequence for this immunogen was taken from within the described region.

Specificity

Antibody reacts with both NAT1 and NAT2

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for NAT2 Antibody

Western Blot: NAT2 Antibody [NBP1-59905]

Western Blot: NAT2 Antibody [NBP1-59905]

Western Blot: NAT2 Antibody [NBP1-59905] - Jurkat cell lysate, Antibody Titration: 2.5ug/ml
Western Blot: NAT2 Antibody [NBP1-59905]

Western Blot: NAT2 Antibody [NBP1-59905]

Western Blot: NAT2 Antibody [NBP1-59905]

Applications for NAT2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NAT2

NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.

Alternate Names

AAC2N-acetyltransferase type 2, Arylamide acetylase 2, arylamine N-acetyltransferase 2, EC 2.3.1.5, N-acetyltransferase 2 (arylamine N-acetyltransferase), NAT-2, PNAT, Polymorphic arylamine N-acetyltransferase

Gene Symbol

NAT2

Additional NAT2 Products

Product Documents for NAT2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NAT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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