Nav1.7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-75581

Novus Biologicals, part of Bio-Techne
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NBP2-75581
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Nav1.7 Antibodies »

Product Specifications

Immunogen

Synthetic peptide within Human Nav1.7 aa 1-50 / 1,988. (SwissProt: Q15858 Human)

Localization

Cell membrane. Cell projection.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

226 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Nav1.7 Antibody

Immunocytochemistry/ Immunofluorescence: Nav1.7 Antibody [NBP2-75581]

Immunocytochemistry/ Immunofluorescence: Nav1.7 Antibody [NBP2-75581]

Immunocytochemistry/Immunofluorescence: Nav1.7 Antibody [NBP2-75581] - Staining NaV1.7 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Immunohistochemistry-Paraffin: Nav1.7 Antibody [NBP2-75581]

Immunohistochemistry-Paraffin: Nav1.7 Antibody [NBP2-75581]

Immunohistochemistry-Paraffin: Nav1.7 Antibody [NBP2-75581] - Analysis of paraffin-embedded mouse colon tissue using anti-NaV1.7 beta antibody. Counter stained with hematoxylin.
Flow Cytometry: Nav1.7 Antibody [NBP2-75581]

Flow Cytometry: Nav1.7 Antibody [NBP2-75581]

Flow Cytometry: Nav1.7 Antibody [NBP2-75581] - Analysis of SH-SY5Y cells with NaV1.7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
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Applications for Nav1.7 Antibody

Application
Recommended Usage

Flow Cytometry

1:50-1:100

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH7.4), 0.2% BSA, 50% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nav1.7

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (from SwissProt).

Long Name

Sodium channel protein type 9 subunit alpha

Alternate Names

hNE-Na, Ne-Na, NENA, PN1, SCN9A

Gene Symbol

SCN9A

Additional Nav1.7 Products

Product Documents for Nav1.7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Nav1.7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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