NCOR1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47360

Novus Biologicals, part of Bio-Techne
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NBP2-47360
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NCOR1 Antibodies »

Product Summary for NCOR1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QDPAFGGKHEAPSSPISGQPCGDDQ

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (84%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NCOR1 Antibody

Western Blot: NCOR1 Antibody [NBP2-47360]

Western Blot: NCOR1 Antibody [NBP2-47360]

Western Blot: NCOR1 Antibody [NBP2-47360] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG.
Immunohistochemistry: NCOR1 Antibody [NBP2-47360]

Immunohistochemistry: NCOR1 Antibody [NBP2-47360]

Immunohistochemistry: NCOR1 Antibody [NBP2-47360] - Staining of human rectum shows strong nuclear positivity in glandular cells.

Applications for NCOR1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NCOR1

NCOR encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Long Name

Nuclear Receptor Co-repressor 1

Alternate Names

KIAA1047, N-CoR, TRAC1

Gene Symbol

NCOR1

Additional NCOR1 Products

Product Documents for NCOR1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NCOR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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