Nectin-3/PVRL3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86553

Novus Biologicals, part of Bio-Techne
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NBP1-86553
NBP1-86553-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Nectin-3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSF

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 22904683).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Nectin-3/PVRL3 Antibody

Immunocytochemistry/ Immunofluorescence: Nectin-3/PVRL3 Antibody [NBP1-86553]

Immunocytochemistry/ Immunofluorescence: Nectin-3/PVRL3 Antibody [NBP1-86553]

Immunocytochemistry/Immunofluorescence: Nectin-3/PVRL3 Antibody [NBP1-86553] - Immunofluorescent staining of human cell line U-251 MG shows localization to microtubule organizing center.
Immunohistochemistry-Paraffin: Nectin-3/PVRL3 Antibody [NBP1-86553]

Immunohistochemistry-Paraffin: Nectin-3/PVRL3 Antibody [NBP1-86553]

Immunohistochemistry-Paraffin: Nectin-3/PVRL3 Antibody [NBP1-86553] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Nectin-3/PVRL3 Antibody [NBP1-86553]

Immunohistochemistry-Paraffin: Nectin-3/PVRL3 Antibody [NBP1-86553]

Immunohistochemistry-Paraffin: Nectin-3/PVRL3 Antibody [NBP1-86553] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.
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Applications for Nectin-3/PVRL3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nectin-3

Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.[supplied by OMIM]

Long Name

Poliovirus Receptor Related 3

Alternate Names

CD113, Nectin3, PPR3, PVRL3, PVRR3

Gene Symbol

NECTIN3

Additional Nectin-3 Products

Product Documents for Nectin-3/PVRL3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Nectin-3/PVRL3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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