NEDP1/SENP8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98855

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NEDP1/SENP8 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human NEDP1/SENP8.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for NEDP1/SENP8 Antibody

Immunocytochemistry/ Immunofluorescence: NEDP1/SENP8 Antibody [NBP2-98855]

Immunocytochemistry/ Immunofluorescence: NEDP1/SENP8 Antibody [NBP2-98855]

Immunocytochemistry/Immunofluorescence: NEDP1/SENP8 Antibody [NBP2-98855] - Immunofluorescence staining of NEDP1/SENP8 in HeLa cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-human NEDP1/SENP8 polyclonal antibody (1:1000) at 4C overnight. Then cells were stained with the Alexa Fluor(R)594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to cytoplasm and nucleus.
Immunohistochemistry-Paraffin: NEDP1/SENP8 Antibody [NBP2-98855]

Immunohistochemistry-Paraffin: NEDP1/SENP8 Antibody [NBP2-98855]

Immunohistochemistry-Paraffin: NEDP1/SENP8 Antibody [NBP2-98855] - Immunochemical staining of human NEDP1/SENP8 in human pancreas with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: NEDP1/SENP8 Antibody [NBP2-98855]

Immunohistochemistry-Paraffin: NEDP1/SENP8 Antibody [NBP2-98855]

Immunohistochemistry-Paraffin: NEDP1/SENP8 Antibody [NBP2-98855] - Immunochemical staining of human NEDP1/SENP8 in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
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Applications for NEDP1/SENP8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:300-1:10000

Immunohistochemistry-Paraffin

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NEDP1/SENP8

NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM]

Alternate Names

DEN1, Deneddylase-1, PRSC2, SENP8

Gene Symbol

SENP8

Additional NEDP1/SENP8 Products

Product Documents for NEDP1/SENP8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NEDP1/SENP8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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