NEIL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00079661-D01P

Novus Biologicals, part of Bio-Techne
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H00079661-D01P
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NEIL1 Antibodies »

Product Specifications

Immunogen

NEIL1 (AAH10876.1, 1 a.a. - 390 a.a.) full-length human protein. MPEGPELHLASQFVNEACRALVFGGCVEKSSVSRNPEVPFESSAYRISASARGKELRLILSPLPGAQPQQEPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRFGRWDLGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARSVLEALQQHRPSPELTLSQKIRTKLQNPDLLELCHSVPKEVVQLGGRGYGSESGEEDFAAFRAWLRCYGMPGMSSLQDRHGRTIWFQGDPGPLAPKGRKSRKKKSKATQLSPEDRVEDALPPSKAPSRTRRAKRDLPKRTATQRPEGTSLQQDPEAPTVPKKGRRKGRQAASGHCRPRKVKADIPSLEPEGTSAS

Specificity

Reacts with nei endonuclease VIII-like 1 (E. coli).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NEIL1 Antibody

Western Blot: NEIL1 Antibody [H00079661-D01P]

Western Blot: NEIL1 Antibody [H00079661-D01P]

Western Blot: NEIL1 Antibody [H00079661-D01P] - Analysis of NEIL1 expression in transfected 293T cell line by NEIL1 polyclonal antibody.Lane 1: NEIL1 transfected lysate(43.70 KDa).Lane 2: Non-transfected lysate.

Applications for NEIL1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NEIL1

NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM]

Alternate Names

DNA-(apurinic or apyrimidinic site) lyase Neil1, EC 3.2.2.-, EC 4.2.99.18, endonuclease 8-like 1, endonuclease VIII, Endonuclease VIII-like 1, FLJ22402, FPG1DNA glycosylase/AP lyase Neil1, hFPG1, NEH1, nei endonuclease VIII-like 1 (E. coli), Nei homolog 1, NEI1, Nei-like protein 1

Entrez Gene IDs

79661 (Human)

Gene Symbol

NEIL1

UniProt

AAH10876.1 (Human)

Additional NEIL1 Products

Product Documents for NEIL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NEIL1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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