Neprilysin/CD10 Antibody (CL12448)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15135

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL12448

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Neprilysin/CD10 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a synthetic peptide. Actual immunogen sequence is proprietary information.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Neprilysin/CD10 Antibody (CL12448)

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human small intestine shows strong apical membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human kidney shows strong apical membranous positivity in cells in tubules and cells in glomeruli.
Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human pancreas shows very weak positivity in exocrine glandular cells.
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Applications for Neprilysin/CD10 Antibody (CL12448)

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2), 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neprilysin/CD10

CD10, also known as the Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Alternate Names

CALLA, CD10, Enkephalinase, Leu-19, MME, Neutral Endopeptidase 24.11, NKH1

Gene Symbol

MME

Additional Neprilysin/CD10 Products

Product Documents for Neprilysin/CD10 Antibody (CL12448)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Neprilysin/CD10 Antibody (CL12448)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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