Neuregulin-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57043

Novus Biologicals, part of Bio-Techne
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NBP2-57043
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Neuregulin-2/NRG2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: HVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYNLEERRRATAPPYHDSVDSL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Neuregulin-2 Antibody

Western Blot: Neuregulin-2 Antibody [NBP2-57043]

Western Blot: Neuregulin-2 Antibody [NBP2-57043]

Western Blot: Neuregulin-2 Antibody [NBP2-57043] - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
Immunocytochemistry/ Immunofluorescence: Neuregulin-2 Antibody [NBP2-57043]

Immunocytochemistry/ Immunofluorescence: Neuregulin-2 Antibody [NBP2-57043]

Immunocytochemistry/Immunofluorescence: Neuregulin-2 Antibody [NBP2-57043] - Staining of human cell line U-2 OS shows localization to nucleus & nucleoli. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Neuregulin-2 Antibody [NBP2-57043]

Immunohistochemistry-Paraffin: Neuregulin-2 Antibody [NBP2-57043]

Immunohistochemistry-Paraffin: Neuregulin-2 Antibody [NBP2-57043] - Immunohistochemical staining of human cerebellum shows moderate nuclear positivity in Purkinje cells.

Applications for Neuregulin-2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neuregulin-2/NRG2

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcripts encoding distinct isoforms have been described.

Alternate Names

Don-1, Neuregulin2, NRG2, NTAK

Gene Symbol

NRG2

Additional Neuregulin-2/NRG2 Products

Product Documents for Neuregulin-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neuregulin-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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