Neuritin Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77282

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Neuritin Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 20 amino acid synthetic peptide from near the center of human neuritin. The immunogen is located within amino acids 70 - 120 of Neuritin. Amino Acid Squence: CQEGAKDMWDKLRKESKNLN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Neuritin Antibody - BSA Free

Western Blot: Neuritin AntibodyBSA Free [NBP1-77282]

Western Blot: Neuritin AntibodyBSA Free [NBP1-77282]

Western Blot: Neuritin Antibody [NBP1-77282] - Analysis of neuritin in Daudi cell lysate with neuritin antibody at (A) 5 and (B) 10 ug/mL.
Immunohistochemistry-Paraffin: Neuritin Antibody - BSA Free [NBP1-77282]

Immunohistochemistry-Paraffin: Neuritin Antibody - BSA Free [NBP1-77282]

Immunohistochemistry-Paraffin: Neuritin Antibody [NBP1-77282] - Analysis of Neuritin in human brain tissue with Neuritin antibody at 2.5 ug/ml.
Immunohistochemistry-Paraffin: Neuritin Antibody - BSA Free [NBP1-77282]

Immunohistochemistry-Paraffin: Neuritin Antibody - BSA Free [NBP1-77282]

Immunohistochemistry-Paraffin: Neuritin Antibody [NBP1-77282] - Neuritin in mouse heart tissue with Neuritin antibody at 5 ug/mL.
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Applications for Neuritin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

5-10 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neuritin

As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.

Alternate Names

NRN1

Gene Symbol

NRN1

UniProt

NP_057672

Additional Neuritin Products

Product Documents for Neuritin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neuritin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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