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Neurofibromin 1 Antibody (CL11773)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21202

Novus Biologicals, part of Bio-Techne
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NBP3-21202-100ul
NBP3-21202-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL11773

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Neurofibromin 1 Antibody (CL11773)

Immunogen

This antibody was developed against a Synthetic Peptide of P21359. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Neurofibromin 1 Antibody (CL11773)

Immunocytochemistry/Immunofluorescence: Neurofibromin 1 Antibody [NBP3-21202] -

Immunocytochemistry/Immunofluorescence: Neurofibromin 1 Antibody [NBP3-21202] -

Staining of U-2 OS cells using the Anti-NF1 monoclonal antibody, showing specific staining in nucleoplasm in green. Microtubule probe is visualized in red.

Applications for Neurofibromin 1 Antibody (CL11773)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neurofibromin 1

Neurofibromin 1 (NF1) is a suspected negative regulator of the ras signal transduction pathway. Neurofibromin is known to regulate the GTPase HRAS, causing the hydrolyzation and inactivation of GTP. Defects in NF1 lead to Neurofibromatosis disease, Recklinghausen disease or Watson disease. Neurofibromin has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence.

Alternate Names

DKFZp686J1293, FLJ21220, Neurofibromatosis-related protein NF-1, neurofibromin, neurofibromin 1, NFNS, VRNF, WSS

Gene Symbol

NF1

Additional Neurofibromin 1 Products

Product Documents for Neurofibromin 1 Antibody (CL11773)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Neurofibromin 1 Antibody (CL11773)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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