Neurofibromin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37914

Novus Biologicals, part of Bio-Techne
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NBP2-37914-25ul
NBP2-37914
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Neurofibromin 1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ALLVLRQLDSIDLWNPDAPGETF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Neurofibromin 1 Antibody

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914]

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914]

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914]

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914]

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914] - Staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914]

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914]

Immunohistochemistry-Paraffin: Neurofibromin 1 Antibody [NBP2-37914] - Staining of human placenta shows moderate to strong granular cytoplasmic positivity in trophoblastic cells.
View 1 more images

Applications for Neurofibromin 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neurofibromin 1

Neurofibromin 1 (NF1) is a suspected negative regulator of the ras signal transduction pathway. Neurofibromin is known to regulate the GTPase HRAS, causing the hydrolyzation and inactivation of GTP. Defects in NF1 lead to Neurofibromatosis disease, Recklinghausen disease or Watson disease. Neurofibromin has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence.

Alternate Names

DKFZp686J1293, FLJ21220, Neurofibromatosis-related protein NF-1, neurofibromin, neurofibromin 1, NFNS, VRNF, WSS

Gene Symbol

NF1

UniProt

P21359 (Human)

Additional Neurofibromin 1 Products

Product Documents for Neurofibromin 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neurofibromin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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