Neurturin Antibody (32E21) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22024

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 32E21

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all Neurturin Antibodies »

Product Specifications

Immunogen

Human recombinant Neurturin

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Neurturin Antibody (32E21) - Azide and BSA Free

Western Blot: Neurturin Antibody (32E21)Azide and BSA Free [NBP2-22024]

Western Blot: Neurturin Antibody (32E21)Azide and BSA Free [NBP2-22024]

Western Blot: Neurturin Antibody (32E21) [NBP2-22024] - Lysates of HEK293 cells overexpressing human Neurturin.

Applications for Neurturin Antibody (32E21) - Azide and BSA Free

Application
Recommended Usage

ELISA

1:1000-1:2000

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neurturin

Neurturin (NTN) is a member of the GDNF family of neurotrophic factors. This protein is a potent survival factor for several populations of central and peripheral neurons in mature and developing rodents. FUNCTION: Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. SUBUNIT: Homodimer; disulfide-linked. SUBCELLULAR LOCATION: Secreted protein. DISEASE: Defects in NRTN are a cause of Hirschsprung disease (HSCR). In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. SIMILARITY: Belongs to the TGF-beta family. GDNF subfamily.

Alternate Names

NRTN, NTN

Gene Symbol

NRTN

UniProt

Q99748

Additional Neurturin Products

Product Documents for Neurturin Antibody (32E21) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Neurturin Antibody (32E21) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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