Neurturin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-68153

Novus Biologicals, part of Bio-Techne
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NB100-68153
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Neurturin Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-DVHSRYHTLQELSARE corresponding to C-Terminus according to Uniprot Mouse NP_032764.1.

Epitope

DVHSRYHTLQELSARE

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Neurturin Antibody

Western Blot: Neurturin Antibody [NB100-68153]

Western Blot: Neurturin Antibody [NB100-68153]

Western Blot: Neurturin Antibody [NB100-68153] - Analysis of Neurturin (mouse) antibody using this antibody at 0.1 ug/ml in mouse brain lysate.

Applications for Neurturin Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 22-23 kDa band observed in mouse brain and rat brain lysates (calculated MW of 22.4 kDa band according to mouse NP_032764.1). An additional very strong band of unknown identity was also consistently observed at 50 kDa. This band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Neurturin

TGF-beta with neurturin and persephin are required for the induction of dopaminergic neurons, whereas GDNF is required for regulating and/or maintaining a differentiated neuronal phenotype. Neurturin-mediated Ret signaling is critical to normal retinal development and function. This study revealed the complexity of postnatal maturation of urogenital innervation, with each organ showing a distinct chronology of innervation and different requirement for neurturin. Transduction-function role for GFR alpha2/neurturin signaling in a specific class of sensory neurons.

Alternate Names

NRTN, NTN

Entrez Gene IDs

18188 (Mouse); 84423 (Rat)

Gene Symbol

NRTN

UniProt

NP_032764.1 (Mouse)

Additional Neurturin Products

Product Documents for Neurturin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Neurturin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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