NF2/Merlin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-93527

Novus Biologicals, part of Bio-Techne
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NB100-93527
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Key Product Details

Species Reactivity

Human, Zebrafish

Applications

Immunohistochemistry, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all NF2/Merlin Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EKSKHLQDQLK corresponding to internal region according to Uniprot Zebrafish NP_998116.1.

Epitope

C-EKSKHLQDQLK

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NF2/Merlin Antibody

Immunohistochemistry: NF2/Merlin Antibody [NB100-93527]

Immunohistochemistry: NF2/Merlin Antibody [NB100-93527]

Immunohistochemistry: NF2/Merlin Antibody [NB100-93527] - Staining (5µg/ml) of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-Staining.

Applications for NF2/Merlin Antibody

Application
Recommended Usage

Immunohistochemistry

5 ug/ml

Peptide ELISA

Detection limit 1:32000
Application Notes
IHC-P: An anonymous customer has reported successful usage on zebrafish brain cortex.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NF2/Merlin

Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.

Long Name

Neurofibromin 2

Alternate Names

ACN, BANF, Merlin, SCH, Schwannomerlin, Schwannomin

Entrez Gene IDs

4771 (Human)

Gene Symbol

NF2

UniProt

NP_998116.1 (Zebrafish)

Additional NF2/Merlin Products

Product Documents for NF2/Merlin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NF2/Merlin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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