NFKBIL2 Antibody (377)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43742

Novus Biologicals, part of Bio-Techne
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NBP2-43742
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 377

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NFKBIL2 Antibodies »

Product Summary for NFKBIL2 Antibody (377)

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human NFKBIL2. The exact sequence is proprietary.

Reactivity Notes

Mouse (83%), Rat (82%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

151 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NFKBIL2 Antibody (377)

Western Blot: NFKBIL2 Antibody (377) [NBP2-43742]

Western Blot: NFKBIL2 Antibody (377) [NBP2-43742]

Western Blot: NFKBIL2 Antibody (377) [NBP2-43742] - Analysis of A. 30 ug 293T whole cell lysate/extract B. 30 ug A431 whole cell lysate/extract C. 30 ug HeLa whole cell lysate/extract D. 30 ug HepG2 whole cell lysate/extract 5 % SDS-PAGE NFKBIL2 antibody [377] dilution: 1:1000.

Applications for NFKBIL2 Antibody (377)

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NFKBIL2

Sharing some sequence similarities with IKBKB, NF-kappa-B inhibitor-like protein 2 (NFKBIL2) belongs to the Tonsoku family. Also known as TONSL, the protein encoded by this gene may bind NF-kappa-B complex and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Additionally, NFKBIL2 is a component of the MMS22L-TONSL complex. Used during DNA replication, this complex is essential for promoting homologous recombination repair of replication fork double strand breaks. NFKBIL2 is known to interact with MMS22L, MCM4, SSRP1, GSK3B and MCM2. Diseases associated with this gene include t-cell leukemia, psoriasis, breast cancer, atherosclerosis, leukemia and immunodeficiency.

Alternate Names

IkappaBR, I-kappa-B-related protein, IKBRFLJ40087, Inhibitor of kappa B-related protein, NF-kappa-B inhibitor-like protein 2, NFKBIL2tonsoku-like protein, Nuclear factor of kappa light polypeptide gene enhancer in B-cellsinhibitor-like 2ikappaBR, tonsoku-like, DNA repair protein

Gene Symbol

TONSL

Additional NFKBIL2 Products

Product Documents for NFKBIL2 Antibody (377)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NFKBIL2 Antibody (377)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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