NFRKB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85096

Novus Biologicals, part of Bio-Techne
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NBP1-85096
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NFRKB Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SLPMLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLWLETKDQAFCKQENEDSSDATTPVPRVRTDYVVRPS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NFRKB Antibody

Immunocytochemistry/ Immunofluorescence: NFRKB Antibody [NBP1-85096]

Immunocytochemistry/ Immunofluorescence: NFRKB Antibody [NBP1-85096]

Immunocytochemistry/Immunofluorescence: NFRKB Antibody [NBP1-85096] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleus.
Immunohistochemistry-Paraffin: NFRKB Antibody [NBP1-85096]

Immunohistochemistry-Paraffin: NFRKB Antibody [NBP1-85096]

Immunohistochemistry-Paraffin: NFRKB Antibody [NBP1-85096] - Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts.

Applications for NFRKB Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:20
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NFRKB

NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.

Alternate Names

DKFZp547B2013, DNA-binding protein R kappa-B, INO80 complex subunit G, INO80GDNA-binding protein R kappa B, nuclear factor related to kappaB binding protein, nuclear factor related to kappa-B-binding protein

Gene Symbol

NFRKB

Additional NFRKB Products

Product Documents for NFRKB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NFRKB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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