Nicotinic Acetylcholine Receptor beta 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-60788

Novus Biologicals, part of Bio-Techne
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NBP2-60788
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Nicotinic Acetylcholine R beta 4/CHRNB4 Antibodies »

Product Specifications

Immunogen

Fusion protein from the cytoplasmic loop of the beta 4 subunit of rat nAChR. Accession # Q8R493

Specificity

Specific for endogenous levels of the ~52 kDa Nicotinic Acetylcholine Receptor beta 4 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Nicotinic Acetylcholine Receptor beta 4 Antibody

Western Blot: Nicotinic Acetylcholine Receptor beta 4 Antibody [NBP2-60788]

Western Blot: Nicotinic Acetylcholine Receptor beta 4 Antibody [NBP2-60788]

Western Blot: Nicotinic Acetylcholine Receptor beta 4 Antibody [NBP2-60788] - Western blot of mouse habenula lysate showing specificimmunolabeling of the ~52 kDa nAChR-Beta-4 protein.

Applications for Nicotinic Acetylcholine Receptor beta 4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10 mM HEPES (pH 7.5), 0.15 M NaCl, 0.1 mg/mL BSA, 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Nicotinic Acetylcholine R beta 4/CHRNB4

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero) pentamers composed of homologous subunits. After binding acetylcholine, the nAChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Long Name

Nicotinic Acetylcholine Receptor beta 4

Alternate Names

CHRNB4, NAChRB4

Gene Symbol

CHRNB4

Additional Nicotinic Acetylcholine R beta 4/CHRNB4 Products

Product Documents for Nicotinic Acetylcholine Receptor beta 4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Nicotinic Acetylcholine Receptor beta 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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