NK1R Antibody (9T1W2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16461

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16461-100ul
NBP3-16461-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 9T1W2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NK1R Antibodies »

Product Summary for NK1R Antibody (9T1W2)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-407 of human NK1R (NK1R) (P25103). YNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NK1R Antibody (9T1W2)

Western Blot: NK1R Antibody (9T1W2) [NBP3-16461]

Western Blot: NK1R Antibody (9T1W2) [NBP3-16461]

Western Blot: NK1R Antibody (9T1W2) [NBP3-16461] - Western blot analysis of extracts of various cell lines, using NK1R (NK1R) Rabbit mAb (NBP3-16461) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
Western Blot: NK1R Antibody (9T1W2) [NBP3-16461]

Western Blot: NK1R Antibody (9T1W2) [NBP3-16461]

Western Blot: NK1R Antibody (9T1W2) [NBP3-16461] - Western blot analysis of extracts of various cell lines, using NK1R (NK1R) Rabbit mAb (NBP3-16461) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for NK1R Antibody (9T1W2)

Application
Recommended Usage

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NK1R

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Long Name

Neurokinin-1 Receptor

Alternate Names

SPR, TAC1R, TACR1

Gene Symbol

TACR1

Additional NK1R Products

Product Documents for NK1R Antibody (9T1W2)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NK1R Antibody (9T1W2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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