NK3R/TACR3/Neurokinin B Receptor Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06055

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NK3R/TACR3 Antibodies »

Product Summary for NK3R/TACR3/Neurokinin B Receptor Antibody

Immunogen

Produced in rabbits immunized with E. coli-derived Human NK3R/TACR3/Neurokinin B Receptor fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for NK3R/TACR3/Neurokinin B Receptor Antibody

Immunohistochemistry-Paraffin: NK3R/TACR3/Neurokinin B Receptor Antibody [NBP3-06055]

Immunohistochemistry-Paraffin: NK3R/TACR3/Neurokinin B Receptor Antibody [NBP3-06055]

Immunohistochemistry-Paraffin: NK3R/TACR3/Neurokinin B Receptor Antibody [NBP3-06055] - Staining of human TACR3 in human liver with rabbit polyclonal antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: NK3R/TACR3/Neurokinin B Receptor Antibody [NBP3-06055]

Immunohistochemistry-Paraffin: NK3R/TACR3/Neurokinin B Receptor Antibody [NBP3-06055]

Immunohistochemistry-Paraffin: NK3R/TACR3/Neurokinin B Receptor Antibody [NBP3-06055] - Staining of human TACR3 in human kidney with rabbit polyclonal antibody at 1:500 dilution.

Applications for NK3R/TACR3/Neurokinin B Receptor Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NK3R/TACR3

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Long Name

Neurokinin-3 Receptor

Alternate Names

Neurokinin B Receptor, Neuromedin-K Receptor, TAC3RL, TACR3

Gene Symbol

TACR3

Additional NK3R/TACR3 Products

Product Documents for NK3R/TACR3/Neurokinin B Receptor Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NK3R/TACR3/Neurokinin B Receptor Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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