NKG2E/KLRC3 Antibody (3D5)

Novus Biologicals, part of Bio-Techne | Catalog # H00003823-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Flow Cytometry, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 3D5

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NKG2E Antibodies »

Product Specifications

Immunogen

KLRC3 (NP_002252, 132 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GKERRTWEESLQACASKNSSSLLSIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS

Localization

Membrane; Single-pass type II membrane protein.

Specificity

KLRC3 - killer cell lectin-like receptor subfamily C, member 3

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for NKG2E/KLRC3 Antibody (3D5)

Sandwich ELISA: NKG2E/KLRC3 Antibody (3D5) [H00003823-M01] - Detection limit for recombinant GST tagged KLRC3 is approximately 0.3ng/ml as a capture antibody.

Applications for NKG2E/KLRC3 Antibody (3D5)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NKG2E

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Long Name

Natural Killer G2E

Alternate Names

killer cell lectin-like receptor subfamily C, member 3, NK cell receptor E, NKG2-E type II integral membrane protein, NKG2-E-activating NK receptor, NKG2ENKG2-E

Entrez Gene IDs

3823 (Human)

Gene Symbol

KLRC3

OMIM

602892 (Human)

UniProt

NP_002252

Additional NKG2E Products

Product Documents for NKG2E/KLRC3 Antibody (3D5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NKG2E/KLRC3 Antibody (3D5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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