NKIRAS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19545

Novus Biologicals, part of Bio-Techne
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NBP2-19545
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Chicken (92%), Mouse (98%), Primate (99%), Rat (98%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NKIRAS2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human NKIRAS2. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (99%).

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NKIRAS2 Antibody

Western Blot: NKIRAS2 Antibody [NBP2-19545]

Western Blot: NKIRAS2 Antibody [NBP2-19545]

Western Blot: NKIRAS2 Antibody [NBP2-19545] - Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE gel, diluted at 1:500.
Immunohistochemistry-Paraffin: NKIRAS2 Antibody [NBP2-19545]

Immunohistochemistry-Paraffin: NKIRAS2 Antibody [NBP2-19545]

Immunohistochemistry-Paraffin: NKIRAS2 Antibody [NBP2-19545] - Immunohistochemical analysis of paraffin-embedded MCF7 xenograft, using antibody at 1:100 dilution.

Applications for NKIRAS2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NKIRAS2

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB

Alternate Names

DKFZP434N1526, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2, KBRAS2DKFZp434N1526, MGC74742, NF-kappa-B inhibitor-interacting Ras-like protein 2, NFKB inhibitor interacting Ras-like 2, NFKB inhibitor interacting Ras-like protein 2

Gene Symbol

NKIRAS2

UniProt

Q9NYR9 (Human)

Additional NKIRAS2 Products

Product Documents for NKIRAS2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for NKIRAS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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