NME6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81587

Novus Biologicals, part of Bio-Techne
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NBP1-81587
NBP1-81587-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NME6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAGTGGLGPA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NME6 Antibody

Immunocytochemistry/ Immunofluorescence: NME6 Antibody [NBP1-81587]

Immunocytochemistry/ Immunofluorescence: NME6 Antibody [NBP1-81587]

Immunocytochemistry/Immunofluorescence: NME6 Antibody [NBP1-81587] - Staining of human cell line A-431 shows localization to vesicles.Antibody staining is shown in green.
Immunohistochemistry-Paraffin: NME6 Antibody [NBP1-81587]

Immunohistochemistry-Paraffin: NME6 Antibody [NBP1-81587]

Immunohistochemistry-Paraffin: NME6 Antibody [NBP1-81587] - Staining of human bronchus shows strong cytoplasmic positivity in endothelial cells and respiratory epithelial cells.

Applications for NME6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NME6

Belonging to the NDK family, NME6 plays an important role in cell growth and is commonly expressed in the kidney, prostate, ovary and intestine. This gene is an inhibitor of p53 induced apoptosis and is a ubiquitous enzyme that catalyzes the transfer of gamma-phosphates. NME6 also phosphorylates nucleoside diphosphates; and is involved in the regulation of development, oncogenic transformation and metastasis. It also plays a major role in the synthesis of nucleoside triphosphates other than ATP. Molecular functions include ATP binding, kinase activity, metal ion binding, nucleoside diphosphate kinase activity, nucleotide binding and transferase activity. Diseases for NME6 include neisseria meningitides, prostatitis, prostate cancer and pneumonia.

Alternate Names

EC 2.7.4.6, Inhibitor of p53-induced apoptosis-alpha, IPIA-alpha, NDK 6, NDP kinase 6, nm23-H6, non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase), nucleoside diphosphate kinase 6

Gene Symbol

NME6

Additional NME6 Products

Product Documents for NME6 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NME6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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