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NMNAT3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27543

Novus Biologicals, part of Bio-Techne
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NBP2-27543

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-QHNIHLAKEPVQNE corresponding to internal region according to NP_835471.1, NP_001186976.1.

Specificity

This antibody is expected to recognize both reported isoforms (NP_835471.1; NP_001186976.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NMNAT3 Antibody

Western Blot: NMNAT3 Antibody [NBP2-27543]

Western Blot: NMNAT3 Antibody [NBP2-27543]

Western Blot: NMNAT3 Antibody [NBP2-27543] - NBP2-27543 (0.1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for NMNAT3 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 26 kDa band observed in human kidney lysates (calculated MW of 24.1 kDa band according to NP_835471.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NMNAT3

The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).[supplied by OMIM]

Alternate Names

EC 2.7.7.1, EC 2.7.7.18, NaMN adenylyltransferase 3, nicotinamide mononucleotide adenylyltransferase 3, nicotinamide nucleotide adenylyltransferase 3, Nicotinate-nucleotide adenylyltransferase 3, PNAT-3, PNAT3NMN adenylyltransferase 3, Pyridine nucleotide adenylyltransferase 3

Gene Symbol

NMNAT3

Additional NMNAT3 Products

Product Documents for NMNAT3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NMNAT3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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