NOS1AP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1090

Novus Biologicals, part of Bio-Techne
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NB100-1090
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all NOS1AP Antibodies »

Product Summary for NOS1AP Antibody

Immunogen

Peptide with sequence PSKTKYNLVDDGH-C corresponding to N-Terminus according to NP_001158229.1.

Specificity

This antibody is expected to recognise both reported isoforms.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NOS1AP Antibody

Immunohistochemistry: NOS1AP Antibody [NB100-1090]

Immunohistochemistry: NOS1AP Antibody [NB100-1090]

Immunohistochemistry: NOS1AP Antibody [NB100-1090] - (5ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Immunohistochemistry-Paraffin: NOS1AP Antibody [NB100-1090]

Immunohistochemistry-Paraffin: NOS1AP Antibody [NB100-1090]

Immunohistochemistry-Paraffin: NOS1AP Antibody [NB100-1090] - Human Brain

Applications for NOS1AP Antibody

Application
Recommended Usage

Immunohistochemistry

4 - 6 ug/ml

Immunohistochemistry-Paraffin

4 - 6 ug/ml

Peptide ELISA

Detection limit 1:1000
Application Notes
IHC-P: Human brain shows localized cytoplasm staining in the neuronal cells.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NOS1AP

NOS1AP encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. [provided by RefSeq]

Alternate Names

6330408P19Rik, CAPONMGC138500, carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, C-terminal PDZ ligand of neuronal nitric oxide synthase protein, KIAA0464C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON), ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain, nitric oxide synthase 1 (neuronal) adaptor protein, Nitric oxide synthase 1 adaptor protein

Entrez Gene IDs

70729 (Mouse); 192363 (Rat)

Gene Symbol

NOS1AP

UniProt

NP_055512.1 (Human)

Additional NOS1AP Products

Product Documents for NOS1AP Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NOS1AP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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