Notch-4 Antibody (SR3217)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27755

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27755-100ul
NBP3-27755-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR3217

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Notch-4 Antibodies »

Product Summary for Notch-4 Antibody (SR3217)

Immunogen

A synthesized peptide derived from human Notch-4 (Uniprot #: Q99466)

Specificity

Detects endogenous levels of total Notch-4

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

230 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Notch-4 Antibody (SR3217)

Western Blot: Notch-4 Antibody (SR3217) [NBP3-27755] -

Western Blot: Notch-4 Antibody (SR3217) [NBP3-27755] - Western blot analysis of Mouse lung lysate.

Applications for Notch-4 Antibody (SR3217)

Application
Recommended Usage

Flow Cytometry

1:50

Western Blot

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Notch-4

NOTCH4 encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).

Alternate Names

INT3, Notch4

Gene Symbol

NOTCH4

Additional Notch-4 Products

Product Documents for Notch-4 Antibody (SR3217)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Notch-4 Antibody (SR3217)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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