NRAMP2/SLC11A2/DMT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91841

Novus Biologicals, part of Bio-Techne
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NBP1-91841
NBP1-91841-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NRAMP2/SLC11A2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKG

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NRAMP2/SLC11A2/DMT1 Antibody

Immunocytochemistry/ Immunofluorescence: NRAMP2/SLC11A2/DMT1 Antibody [NBP1-91841]

Immunocytochemistry/ Immunofluorescence: NRAMP2/SLC11A2/DMT1 Antibody [NBP1-91841]

Immunocytochemistry/Immunofluorescence: NRAMP2/SLC11A2/DMT1 Antibody [NBP1-91841] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
Immunohistochemistry-Paraffin: NRAMP2/SLC11A2/DMT1 Antibody [NBP1-91841]

Immunohistochemistry-Paraffin: NRAMP2/SLC11A2/DMT1 Antibody [NBP1-91841]

Immunohistochemistry-Paraffin: NRAMP2/SLC11A2/DMT1 Antibody [NBP1-91841] - Staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in neuronal cells.

Applications for NRAMP2/SLC11A2/DMT1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NRAMP2/SLC11A2

The SLC11A2 gene encodes a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body (Hubert and Hentze, 2002 [PubMed 12209011]; Ludwiczek et al., 2007 [PubMed 17293870]).[supplied by OMIM]

Long Name

Natural Resistance-associated Macrophage Protein 2

Alternate Names

DCT1, SLC11A2

Gene Symbol

SLC11A2

Additional NRAMP2/SLC11A2 Products

Product Documents for NRAMP2/SLC11A2/DMT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NRAMP2/SLC11A2/DMT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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