OAS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00004938-D03P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all OAS1 Antibodies »

Product Specifications

Immunogen

OAS1 (AAH00562.1, 1 a.a. - 364 a.a.) full-length human protein. MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGSYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRPPASSLPFIPAPLHEA

Specificity

2',5'-oligoadenylate synthetase 1, 40/46kDa

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for OAS1 Antibody

Western Blot: OAS1 Antibody [H00004938-D03P]

Western Blot: OAS1 Antibody [H00004938-D03P]

Western Blot: OAS1 Antibody [H00004938-D03P] - Analysis of OAS1 expression in transfected 293T cell line by OAS1 polyclonal antibody.Lane 1: OAS1 transfected lysate(40.04 KDa).Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: OAS1 Antibody [H00004938-D03P]

Immunocytochemistry/ Immunofluorescence: OAS1 Antibody [H00004938-D03P]

Immunocytochemistry/Immunofluorescence: OAS1 Antibody [H00004938-D03P] - Analysis of antibody to OAS1 on HeLa cell. Antibody concentration 30 ug/ml.

Applications for OAS1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
This antibody is reactive against mammalian transfected lysate in WB. It has been used for ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: OAS1

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Alternate Names

(2-5')oligo(A) synthase 1,2'-5'-oligoadenylate synthetase 1,2-5A synthase 1,2'-5'-oligoisoadenylate synthetase 1, (2-5')oligo(A) synthetase 1, 2'-5'-oligo A synthetase 1, 2'-5'-oligoadenylate synthase 1, 2'-5'-oligoadenylate synthetase 1 (40-46 kD), 2'-5'-oligoadenylate synthetase 1, 40/46kDa, E18/E16,2-5A synthetase 1, EC 2.7.7, EC 2.7.7.-, IFI-4,2'-5' oligoadenylate synthetase 1 p52 isoform, OIAS2'-5' oligoadenylate synthetase 1 p48 isoform, OIASI, p46/p42 OAS

Entrez Gene IDs

4938 (Human)

Gene Symbol

OAS1

UniProt

AAH00562.1 (Human)

Additional OAS1 Products

Product Documents for OAS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for OAS1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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