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OAS3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85841

Novus Biologicals, part of Bio-Techne
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NBP1-85841
NBP1-85841-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for OAS3 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGCSGLGHPIQLDPNQKTPENSKSLNAVYPRAGSKPPSCP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for OAS3 Antibody

Western Blot: OAS3 Antibody [NBP1-85841]

Western Blot: OAS3 Antibody [NBP1-85841]

Western Blot: OAS3 Antibody [NBP1-85841] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4
Immunocytochemistry/ Immunofluorescence: OAS3 Antibody [NBP1-85841]

Immunocytochemistry/ Immunofluorescence: OAS3 Antibody [NBP1-85841]

Immunocytochemistry/Immunofluorescence: OAS3 Antibody [NBP1-85841] - Staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: OAS3 Antibody [NBP1-85841]

Immunohistochemistry-Paraffin: OAS3 Antibody [NBP1-85841]

Immunohistochemistry-Paraffin: OAS3 Antibody [NBP1-85841] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Applications for OAS3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OAS3

The OAS3 gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in

Alternate Names

(2-5')oligo(A) synthase 3,2'-5'oligoadenylate synthetase p100, 2-5A synthase 3, 2'-5'-oligoadenylate synthase 3, 2'-5'-oligoadenylate synthetase 3, 100kDa, P/OKcl.4, p100 OAS

Gene Symbol

OAS3

Additional OAS3 Products

Product Documents for OAS3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for OAS3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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