OATP1B3/SLCO1B3/OATP8 Antibody (CL3770)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61636

Novus Biologicals, part of Bio-Techne
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NBP2-61636
NBP2-61636-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3770

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all OATP1B3/SLCO1B3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QGKDTKASDNERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAAA

Epitope

EFLNNGEHFVPSAGT

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for OATP1B3/SLCO1B3/OATP8 Antibody (CL3770)

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (CL3770) [NBP2-61636]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (CL3770) [NBP2-61636]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (CL3770) [NBP2-61636] - Staining of human pancreas shows absence of immunoreactivity (negative control).
Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (CL3770) [NBP2-61636]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (CL3770) [NBP2-61636]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (CL3770) [NBP2-61636] - Staining of human liver shows strong membranous immunoreactivity in hepatocytes.

Applications for OATP1B3/SLCO1B3/OATP8 Antibody (CL3770)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
IHC-P, HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OATP1B3/SLCO1B3

The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Long Name

Sodium-independent Organic Anion-transporting Polypeptide 2

Alternate Names

LST2, LST3, OATP8, SLC21A8, SLCO1B3

Gene Symbol

SLCO1B3

Additional OATP1B3/SLCO1B3 Products

Product Documents for OATP1B3/SLCO1B3/OATP8 Antibody (CL3770)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for OATP1B3/SLCO1B3/OATP8 Antibody (CL3770)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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