OATP1B3/SLCO1B3/OATP8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-54739

Novus Biologicals, part of Bio-Techne
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NBP2-54739
NBP2-54739-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all OATP1B3/SLCO1B3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a Recombinant Protein corresponding to amino acids: DVPLSYCNSECNCDESQWEPVCGNNG

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for OATP1B3/SLCO1B3/OATP8 Antibody

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739] - Staining of human liver shows moderate membranous positivity in hepatocytes.
OATP1B3/SLCO1B3/OATP8 Antibody

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739] -

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
OATP1B3/SLCO1B3/OATP8 Antibody

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739] -

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP2-54739] - Staining of human kidney shows no positivity in cells in tubules as expected.
View 1 more images

Applications for OATP1B3/SLCO1B3/OATP8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 -1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OATP1B3/SLCO1B3

The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Long Name

Sodium-independent Organic Anion-transporting Polypeptide 2

Alternate Names

LST2, LST3, OATP8, SLC21A8, SLCO1B3

Gene Symbol

SLCO1B3

Additional OATP1B3/SLCO1B3 Products

Product Documents for OATP1B3/SLCO1B3/OATP8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for OATP1B3/SLCO1B3/OATP8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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