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Key Product Details

Species Reactivity

Validated:

Human, Mouse (Negative)

Cited:

Human

Applications

Validated:

Block/Neutralize, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 17001.31

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant full length protein (Human) expressed in E. coli.

Localization

Secreted

Specificity

Does not cross-react with recombinant human IL-6, IL-11, CNTF, LIF and recombinant mouse OSM.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Endotoxin Level

Endotoxin level is < 0.1 EU/ug antibody as determined by the LAL (Limulus amebocyte lysate) method.

Applications for Oncostatin M/OSM Antibody (17001.31)

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml
Application Notes
The antibody neutralizes the biological activity of recombinant human OSM.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 5% Trehalose

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Oncostatin M/OSM

Oncostatin M is an important growth regulating cytokine that affects variably a number of tumor and normal cells. Oncostatin M exerts inhibitory effects on the growth of A375 melanoma and other cancer cells, but augments the growth of normal fibroblasts, AIDS-related Kaposi sarcoma cells, and other certain cells.

Alternate Names

MGC20461, oncostatin M, oncostatin-M

Entrez Gene IDs

5008 (Human); 18413 (Mouse)

Gene Symbol

OSM

Additional Oncostatin M/OSM Products

Product Documents for Oncostatin M/OSM Antibody (17001.31)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Oncostatin M/OSM Antibody (17001.31)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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