OPA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48669

Novus Biologicals, part of Bio-Techne
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NBP2-48669
NBP2-48669-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all OPA1 Antibodies »

Product Summary for OPA1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for OPA1 Antibody

Western Blot: OPA1 Antibody [NBP2-48669]

Western Blot: OPA1 Antibody [NBP2-48669]

Western Blot: OPA1 Antibody [NBP2-48669] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11
Lane 2: Human cell line RT-4
Lane 3: Human cell line U-251MG sp
Immunohistochemistry-Paraffin: OPA1 Antibody [NBP2-48669]

Immunohistochemistry-Paraffin: OPA1 Antibody [NBP2-48669]

Immunohistochemistry-Paraffin: OPA1 Antibody [NBP2-48669] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Applications for OPA1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OPA1

OPA1 product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Highly expressed in the retina, OPA1 mutations have been associated with a dominantly inherited optic neuropathy, called optic atrophy type 1, resulting in progressive loss of visual acuity. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene.

OPA1 antibodies are used primarily for vision research.

Long Name

Optic Atrophy Protein 1

Alternate Names

BERHS, EC 3.6.5.5, LargeG, lilr3, MGM1, MTDPS14, NPG, NTG

Gene Symbol

OPA1

Additional OPA1 Products

Product Documents for OPA1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for OPA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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