Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Chicken (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Orai2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human ORAI2. The immunogen is located within the last 50 amino acids of ORAI2. Amino Acid Squence: HKTERHNREIEELHK

Specificity

At least two isoforms of ORAI2 are known to exist; this antibody will detect both isoforms. ORAI antibody is predicted not to cross-react with ORAI1 or ORAI3.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Orai2 Antibody - BSA Free

Western Blot: Orai2 AntibodyBSA Free [NBP1-77283]

Western Blot: Orai2 AntibodyBSA Free [NBP1-77283]

Western Blot: Orai2 Antibody [NBP1-77283] - Analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL.
Immunocytochemistry/ Immunofluorescence: Orai2 Antibody - BSA Free [NBP1-77283]

Immunocytochemistry/ Immunofluorescence: Orai2 Antibody - BSA Free [NBP1-77283]

Immunocytochemistry/Immunofluorescence: Orai2 Antibody [NBP1-77283] - ORAI2 in Jurkat cells with ORAI2 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: Orai2 Antibody - BSA Free [NBP1-77283]

Immunocytochemistry/ Immunofluorescence: Orai2 Antibody - BSA Free [NBP1-77283]

Immunocytochemistry/Immunofluorescence: Orai2 Antibody [NBP1-77283] - ORAI2 in Jurkat cells with ORAI2 antibody at 5 ug/mL.
View 2 more images

Applications for Orai2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5-20 ug/ml

Western Blot

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Orai2

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.

Long Name

Protein orai-2

Alternate Names

C7orf19, CBCIP2, PP1729, TMEM142B

Gene Symbol

ORAI2

UniProt

Q96SN7 (Human)

Additional Orai2 Products

Product Documents for Orai2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Orai2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.