Orexin B/Hypocretin-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17408

Novus Biologicals, part of Bio-Techne
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NBP3-17408-100ul
NBP3-17408-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Orexin B/Hypocretin-2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DCCRQKTCSCRLYELLHGAGNHAAGILTLGK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Orexin B/Hypocretin-2 Antibody

Immunohistochemistry-Paraffin: Orexin B/Hypocretin-2 Antibody [NBP3-17408]

Immunohistochemistry-Paraffin: Orexin B/Hypocretin-2 Antibody [NBP3-17408]

Immunohistochemistry-Paraffin: Orexin B/Hypocretin-2 Antibody [NBP3-17408] - Staining of human hypothalamus shows strong cytoplasmic positivity in neuronal cells.

Applications for Orexin B/Hypocretin-2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Orexin B/Hypocretin-2

Orexin A and orexin B are neuropeptide hormones derived from proteolytic processing of the same orexin precursor protein. Orexins are named for their orexigenic-inducing (orexis; Greek for appetite) activity. They are released from the hypothalamus and are involved in the regulation of sleeping patterns, feeding, and metabolism. Orexins A and B are less than 50% amino acid identical. Orexin A is a ligand for two 7-transmembrane orexin receptors, OX1R and OX2R, while orexin B preferentially binds OX2R. Defects in the orexin precursor are a cause of narcolepsy in humans.

Alternate Names

Hcrt2, Hypocretin-2, Hypocretin2, PPORX, PPOX

Gene Symbol

HCRT

Additional Orexin B/Hypocretin-2 Products

Product Documents for Orexin B/Hypocretin-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Orexin B/Hypocretin-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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