Osteoprotegerin/TNFRSF11B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25031

Novus Biologicals, part of Bio-Techne
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NBP3-25031
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Osteoprotegerin/TNFRSF11B Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Osteoprotegerin/TNFRSF11B using the following amino acid sequence: SSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLMESLPGKKVGAEDIE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Osteoprotegerin/TNFRSF11B Antibody

Osteoprotegerin/TNFRSF11B Antibody Immunocytochemistry/Immunofluorescence: Osteoprotegerin/TNFRSF11B Antibody [NBP3-25031]

Immunocytochemistry/Immunofluorescence: Osteoprotegerin/TNFRSF11B Antibody [NBP3-25031]

Staining of human cell line BJ [Human fibroblast] shows localization to the Golgi apparatus.

Applications for Osteoprotegerin/TNFRSF11B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Osteoprotegerin/TNFRSF11B

Osteoprotegerin is encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]

Alternate Names

OCIF, TNFRSF11B

Gene Symbol

TNFRSF11B

Additional Osteoprotegerin/TNFRSF11B Products

Product Documents for Osteoprotegerin/TNFRSF11B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Osteoprotegerin/TNFRSF11B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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