OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-75913JF525

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Block/Neutralize, Flow Cytometry

Label

Janelia Fluor 525

Antibody Source

Monoclonal Human IgG1 kappa Clone # R4930 (Oxelumab)

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all OX40 Ligand/TNFSF4 Antibodies »

Product Summary for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Janelia Fluor® 525]

Immunogen

Oxelumab binds to human OX40L, the ligand of OX40, stimulatory receptor that is expressed on activated T cells, natural killer (NK) cells and natural killer T (NKT) cells.

Specificity

Binds to human OX40L.

Clonality

Monoclonal

Host

Human

Isotype

IgG1 kappa

Applications for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Janelia Fluor® 525]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: OX40 Ligand/TNFSF4

CD252 is a 35 kD member of the TNF superfamily also known as OX40L and CD134L. The OX40 ligand is expressed on activated B cells and antigen presenting cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to increase proliferation and IL-2 production, and to enhance proliferation and immunoglobulin secretion in activated B cells. The RM134L antibody can inhibit OX40/OX40 ligand interactions and block the costimulatory activity of OX40L.

Alternate Names

CD252, gp34, TNFSF4

Gene Symbol

TNFSF4

Additional OX40 Ligand/TNFSF4 Products

Product Documents

Product Datasheets

Certificate of Analysis

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Product Specific Notices for OX40 Ligand/TNFSF4 Antibody (R4930 (Oxelumab)) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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