Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, T Cell Stimulation

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG1 Clone # AP-MAB0833

Format

Azide and BSA Free

Concentration

1.0 mg/ml

View all OX40/TNFRSF4 Antibodies »

Product Specifications

Immunogen

Recombinant mouse OX-40 protein

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Applications for OX40/TNFRSF4 Antibody (AP-MAB0833) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500
Application Notes
Flow Cytometry, Immunohistochemistry-Frozen, Stimulation of T cell proliferation and does not blocking the binding of CD134(OX-40) to its ligand. This antibody is CyTOF ready.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: OX40/TNFRSF4

CD134 is a type I integral membrane protein, also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases. This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with Recombinant mouse OX-40 protein.

Alternate Names

ACT-135, ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, Ly-70, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, TNFRSF4, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, Txgp1, TXGP1L, TXGP1LOX40 antigen

Entrez Gene IDs

22163 (Mouse)

Gene Symbol

TNFRSF4

Additional OX40/TNFRSF4 Products

Product Documents for OX40/TNFRSF4 Antibody (AP-MAB0833) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for OX40/TNFRSF4 Antibody (AP-MAB0833) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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