Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG1 Clone # OX-86

Concentration

1 mg/ml

View all OX40/TNFRSF4 Antibodies »

Product Specifications

Immunogen

CHO cells transfected with murine OX40

Localization

Cell Membrane. Type I membrane protein.

Specificity

NB100-64847 recognises murine OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Scientific Data Images for OX40/TNFRSF4 Antibody (OX-86)

Flow Cytometry: OX40/TNFRSF4 Antibody (OX-86) - BSA Free [NB100-64847]

Flow Cytometry: OX40/TNFRSF4 Antibody (OX-86) - BSA Free [NB100-64847]

Flow Cytometry: OX40/TNFRSF4 Antibody (OX-86) [NB100-64847] - Staining of Concanavalin A stimulated mouse spleen cells with Rat anti Mouse
Flow Cytometry: OX40/TNFRSF4 Antibody (OX-86) - BSA Free [NB100-64847]

Flow Cytometry: OX40/TNFRSF4 Antibody (OX-86) - BSA Free [NB100-64847]

Flow Cytometry: OX40/TNFRSF4 Antibody (OX-86) [NB100-64847] - Staining of Concanavalin A stimulated mouse spleen cells with Rat anti Mouse CD134: RPE.

Applications for OX40/TNFRSF4 Antibody (OX-86)

Application
Recommended Usage

Flow Cytometry

1:10-1:50

Immunohistochemistry-Frozen

1:10-1:500

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OX40/TNFRSF4

The OX40 receptor is also known as CD134, ACT35, and tumour necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.

Alternate Names

ACT-135, ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, Ly-70, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, TNFRSF4, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, Txgp1, TXGP1L, TXGP1LOX40 antigen

Entrez Gene IDs

22163 (Mouse)

Gene Symbol

TNFRSF4

UniProt

P47741

Additional OX40/TNFRSF4 Products

Product Documents for OX40/TNFRSF4 Antibody (OX-86)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for OX40/TNFRSF4 Antibody (OX-86)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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