OXTR Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-02334

Novus Biologicals, part of Bio-Techne
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NBP1-02334
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Predicted:

Primate (95%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all OXTR Antibodies »

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from C-terminal cytoplasmic domain of human OXTR.

Epitope

C-Terminus cytoplasmic domain

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 18755161). Predicted cross-reactivity based on sequence identity: Gorilla (95%), Gibbon (95%), Marmoset (89%), Mouse (84%), Canien (84%).

Specificity

Human OXTR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for OXTR Antibody - BSA Free

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02334]

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02334]

Immunohistochemistry-Paraffin: OXTR Antibody - BSA Free [NBP1-02334] - Staining of human uterus, pregnant. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 40 ug/ml.

Applications for OXTR Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

40 ug/ml

Immunohistochemistry-Paraffin

40 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: OXTR

The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.

Long Name

Oxytocin Receptor

Alternate Names

OT-R

Entrez Gene IDs

5021 (Human)

Gene Symbol

OXTR

UniProt

P30559

Additional OXTR Products

Product Documents for OXTR Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for OXTR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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