p19 INK4d Antibody (2E10)

Novus Biologicals, part of Bio-Techne | Catalog # H00001032-M08

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
H00001032-M08
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 2E10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all p19 INK4d Antibodies »

Product Specifications

Immunogen

CDKN2D (AAH01822, 1 a.a. ~ 166 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGVSPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL

Specificity

CDKN2D - cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (2E10)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for p19 INK4d Antibody (2E10)

Western Blot: p19 INK4d Antibody (2E10) [H00001032-M08]

Western Blot: p19 INK4d Antibody (2E10) [H00001032-M08]

Western Blot: p19 INK4d Antibody (2E10) [H00001032-M08] - Analysis of CDKN2D expression in transfected 293T cell line by CDKN2D monoclonal antibody (M08), clone 2E10. Lane 1: CDKN2D transfected lysatE (17.7 KDa). Lane 2: Non-transfected lysate.
Immunoprecipitation: p19 INK4d Antibody (2E10) [H00001032-M08]

Immunoprecipitation: p19 INK4d Antibody (2E10) [H00001032-M08]

Immunoprecipitation: p19 INK4d Antibody (2E10) [H00001032-M08] - Analysis of CDKN2D transfected lysate using anti-CDKN2D monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with CDKN2D rabbit polyclonal antibody.
Sandwich ELISA: p19 INK4d Antibody (2E10) [H00001032-M08] - Detection limit for recombinant GST tagged CDKN2D is 0.1 ng/ml as a capture antibody.

Applications for p19 INK4d Antibody (2E10)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: p19 INK4d

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq]

Alternate Names

CDK inhibitor p19INK4d, cell cycle inhibitor, Nur77 associating protein, cyclin-dependent kinase 4 inhibitor D, cyclin-dependent kinase 4 inhibitor D p19, cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4), inhibitor of cyclin-dependent kinase 4d, INK4D, p19, p19-INK4d

Entrez Gene IDs

1032 (Human)

Gene Symbol

CDKN2D

UniProt

AAH01822 (Human)

Additional p19 INK4d Products

Product Documents for p19 INK4d Antibody (2E10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for p19 INK4d Antibody (2E10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.