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P2X1/P2RX1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25034

Novus Biologicals, part of Bio-Techne
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NBP3-25034

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein P2X1/P2RX1 using the following amino acid sequence: LFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for P2X1/P2RX1 Antibody

P2X1/P2RX1 Antibody Immunocytochemistry/Immunofluorescence: P2X1/P2RX1 Antibody [NBP3-25034]

Immunocytochemistry/Immunofluorescence: P2X1/P2RX1 Antibody [NBP3-25034]

Staining of human cell line U2OS shows localization to endoplasmic reticulum.

Applications for P2X1/P2RX1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2X1/P2RX1

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Long Name

P2X Purinergic Receptor 1

Alternate Names

P2RX1, P2XMR

Gene Symbol

P2RX1

Additional P2X1/P2RX1 Products

Product Documents for P2X1/P2RX1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for P2X1/P2RX1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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