P2X7/P2RX7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82738

Novus Biologicals, part of Bio-Techne
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NBP1-82738
NBP1-82738-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all P2X7/P2RX7 Antibodies »

Product Summary for P2X7/P2RX7 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for P2X7/P2RX7 Antibody

Western Blot: P2X7/P2RX7 Antibody [NBP1-82738]

Western Blot: P2X7/P2RX7 Antibody [NBP1-82738]

Western Blot: P2X7/P2RX7 Antibody [NBP1-82738] - Analysis in human cell lines SK-MEL-30 and Caco-2 using anti-P2RX7 antibody. Corresponding P2RX7 RNA-seq data are presented for the same cell lines. Loading control: anti-GAPDH.
Western Blot: P2X7/P2RX7 Antibody [NBP1-82738]

Western Blot: P2X7/P2RX7 Antibody [NBP1-82738]

Western Blot: P2X7/P2RX7 Antibody [NBP1-82738] - Analysis using Anti-P2RX7 antibody NBP1-82738 (A) shows similar pattern to independent antibody NBP1-82739 (B).
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-82738]

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-82738]

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-82738] - Staining of human cerebral cortex shows moderate positivity in neuropil.

Applications for P2X7/P2RX7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2X7/P2RX7

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Long Name

P2X Purinergic Receptor 7

Alternate Names

P2RX7

Gene Symbol

P2RX7

Additional P2X7/P2RX7 Products

Product Documents for P2X7/P2RX7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for P2X7/P2RX7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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