P2Y12/P2RY12 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89673

Novus Biologicals, part of Bio-Techne
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NBP1-89673
NBP1-89673-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all P2Y12/P2RY12 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LTNRQPRDKNVKKCSFLKSEFGLVWHEIV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for P2Y12/P2RY12 Antibody

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673] - Staining in human cerebral cortex and skeletal muscle tissues using NBP1-89673 antibody. Corresponding P2RY12 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673] - Staining of human cerebellum shows strong positivity in microglia.
Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NBP1-89673] - Staining of human cerebral cortex shows strong positivity in microglia.
View 2 more images

Applications for P2Y12/P2RY12 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2Y12/P2RY12

P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries. Cognate

Long Name

P2Y Purinergic Receptor 12

Alternate Names

ADPG-R, HORK3, P2RY12, SP1999

Gene Symbol

P2RY12

Additional P2Y12/P2RY12 Products

Product Documents for P2Y12/P2RY12 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for P2Y12/P2RY12 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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