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P2Y12/P2RY12 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS3742

Novus Biologicals, part of Bio-Techne
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NLS3742

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human P2Y12/P2RY12.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (88%), Marmoset (88%), Porcine (82%).

Specificity

Human P2Y12/P2RY12. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for P2Y12/P2RY12 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: P2Y12/P2RY12 Antibody - BSA Free [NLS3742]

Immunocytochemistry/ Immunofluorescence: P2Y12/P2RY12 Antibody - BSA Free [NLS3742]

Immunocytochemistry/Immunofluorescence: P2Y12/P2RY12 Antibody [NLS3742] - Analysis of anti-P2RY12 / P2Y12 antibody with HEK293 human embryonic kidney cells
Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody - BSA Free [NLS3742]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody - BSA Free [NLS3742]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NLS3742] - Ovary, Carcinoma
Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody - BSA Free [NLS3742]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody - BSA Free [NLS3742]

Immunohistochemistry-Paraffin: P2Y12/P2RY12 Antibody [NLS3742] - Analysis of anti-P2RY12 / P2Y12 antibody with human brain, glioblastoma.

Applications for P2Y12/P2RY12 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

32 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: P2Y12/P2RY12

P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries. Cognate

Long Name

P2Y Purinergic Receptor 12

Alternate Names

ADPG-R, HORK3, P2RY12, SP1999

Entrez Gene IDs

64805 (Human)

Gene Symbol

P2RY12

Additional P2Y12/P2RY12 Products

Product Documents for P2Y12/P2RY12 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for P2Y12/P2RY12 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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